Structure/nerve membrane effect relationships of some local anaesthetics.
نویسندگان
چکیده
Data on electron structure and octanol-water partition coefficients of certain local anaesthetics are compared with the capacity of reversibly block the action potential of the frog sciatic nerve. Some active parts in the molecules of these substances have been shown to be primarily involved in the action of local anaesthetics.
منابع مشابه
PHARMACOLOGICAL STUDIES ON NOVEL BASIC AMINOALKYL ARYL ETHERS AS POTENTIAL LOCAL ANAESTHETICS
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ورودعنوان ژورنال:
- General physiology and biophysics
دوره 5 4 شماره
صفحات -
تاریخ انتشار 1986